Linaclotide is used to treat chronic constipation, or chronic irritable bowel syndrome (IBS) in people who have had constipation as the main symptom. Show
Linaclotide may also be used for purposes not listed in this medication guide. usesWhat is Linzess (Linaclotide) used for?
warningsWhat is the most important information I should know about Linzess (Linaclotide)?You should not use linaclotide if you are allergic to it, or if you have:
Linaclotide is not approved for use by anyone younger than 18 years old. Linaclotide should not be given to a child younger than 6 years old. Linaclotide can cause severe diarrhea and fatal dehydration in a child. Do not give this medicine to any child or teenager without the advice of a doctor. Tell your doctor if you are pregnant or breastfeeding. User Reviews & RatingOverall rating for Linzess (Linaclotide)3.2 out of 5 (213 Linzess (Linaclotide) Reviews)Side Effects Easy to Use 4.1Effectiveness 3.4Read Linzess (Linaclotide) ReviewsSide EffectsWhat are the side effects of Linzess (Linaclotide)?Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using linaclotide and call your doctor at once if you have:
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. Pregnancy & BreastfeedingCan I take Linzess (Linaclotide) if I’m pregnant or breastfeeding?C Risk cannot be ruled out Based on FDA pregnancy categories Tell your doctor if you are pregnant or breastfeeding. InteractionsWhat drugs and food should I avoid while taking Linzess (Linaclotide)?Follow your doctor's instructions about any restrictions on food, beverages, or activity. Dosage Guidelines & TipsHow to take Linzess (Linaclotide)?Use Linzess (Linaclotide) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Take linaclotide in the morning on an empty stomach, at least 30 minutes before your first meal. Swallow the capsule whole and do not crush, chew, break, or open it. If you cannot swallow a capsule whole, open it and sprinkle the medicine into a spoonful of applesauce or bottled water. Swallow the mixture right away without chewing. Do not save it for later use. Even if you have taken this medicine with applesauce, wait at least 30 minutes before eating a full meal. If needed, medicine from the linaclotide capsule may be given through a nasogastric (NG) or gastronomy tube. Carefully follow instructions for mixing medicine from the capsule with applesauce or water, or giving the medicine through a feeding tube. Ask your doctor or pharmacist if you have any questions. It may take up to 2 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve. Store at room temperature away from moisture and heat. Keep the tablets in their original container, along with the packet or canister of moisture-absorbing preservative. Keep this medicine out of the reach of children. Linaclotide can be fatal to a child who accidentally swallows this medicine. Seek emergency medical attention if this happens. What should I do if I missed a dose of Linzess (Linaclotide)? Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time. Overdose SignsWhat happens if I overdose on Linzess (Linaclotide)?If you think you or someone else may have overdosed on: Linzess (Linaclotide), call your doctor or the Poison Control center (800) 222-1222If someone collapses or isn't breathing after taking Linzess (Linaclotide), call 911 911ImagesFL 145Color: white Shape: capsule Imprint: FL 145 FL 290Color: white Shape: capsule Imprint: FL 290 Find Another DrugSearch prescription drugs, over-the counter medications, and supplementsCLEAR Medical DisclaimerDrugs A-Z provides drug information from Everyday Health and our partners, as well as ratings from our members, all in one place. Cerner Multum™ provides the data within some of the Overview, Uses, Warnings, Side Effects, Pregnancy, Interactions, Dosage, Overdose, and Images sections. The information within all other sections is proprietary to Everyday Health. Read more How long does it take LINZESS 145 to work?When LINZESS is taken daily, constipation relief is typically felt in about 1 week. IBS-C patients may begin to experience relief of belly pain and overall abdominal symptoms* (pain, discomfort, and bloating) in about 1 week, with symptoms typically improving over 12 weeks.
Is LINZESS a laxative or stool softener?LINZESS isn't a laxative. It helps you have more frequent and complete bowel movements, and helps relieve belly pain and overall abdominal symptoms* (pain, discomfort, and bloating) associated with IBS-C.
How quickly does LINZESS produce a bowel movement?When LINZESS is taken daily, your constipation and abdominal symptoms may improve over time. Constipation relief is typically felt in about 1 week.
How often do you take LINZESS 145 mcg?Chronic Idiopathic Constipation (CIC)
The recommended dosage of LINZESS is 145 mcg orally once daily. A dosage of 72 mcg once daily may be used based on individual presentation or tolerability.
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